secobarbital will lower the extent or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch."I used to be looking at what was going on and thinking: 'This is not as good as it has been hyped up for being,' " he claimed.secobarbital will lessen the level or effect of fosaprepitant by influencing hepatic/int… Read More